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2025, Vol: 2, Issue: 3
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Research Article
Online Published: 02 May 2025
 


Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria

Zenas Chisom Agubata, Kizito Bello, Cornelius Omatola, Benjamin Adaji, Ayodele Olubukola Olusola.


Abstract
Aim: Syphilis, a sexually transmitted infection caused by Treponema pallidum, has been shown to increase susceptibility to HIV/AIDS and vice versa, due to immune activation and ulcerative lesions that facilitate viral entry. This study aims to provide current data on syphilis sero-prevalence among HIV patients receiving ART at Kogi State Specialist Hospital.
Methods: This study assessed syphilis prevalence among 200 HIV-positive patients on anti-retroviral therapy (ART) at Kogi State Specialist Hospital, Lokoja, Nigeria. Anti-Treponema antibodies were detected using a WHO-approved syphilis test kit.
Results: Out of 200 patients tested, 9 (4.5%) were positive for syphilis antibodies. Males (9.83%) and the 50–59 age group (16.67%) showed higher prevalence, though differences in prevalence by gender and age were not statistically significant (p > 0.05). Risk factors such as intravenous drug use and history of ulcer were associated with increased syphilis prevalence.
Conclusions: Routine syphilis screening is recommended for HIV-positive patients to mitigate complications associated with co-infection and improve patient outcomes.

Key words: Key Words: Syphilis, Co-infection, Treponema pallidum, HIV/AIDS, Seroprevalence


 
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How to Cite this Article
Pubmed Style

Agubata ZC, Bello K, Omatola C, Adaji B, Olusola AO. Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. J Biol Res Rev. 2025; 2(3): 130-138. doi:10.5455/JBRR.20241025112618

Web Style

Agubata ZC, Bello K, Omatola C, Adaji B, Olusola AO. Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. https://www.wisdomgale.com/jbrr/?mno=226109 [Access: May 10, 2025]. doi:10.5455/JBRR.20241025112618

AMA (American Medical Association) Style

Agubata ZC, Bello K, Omatola C, Adaji B, Olusola AO. Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. J Biol Res Rev. 2025; 2(3): 130-138. doi:10.5455/JBRR.20241025112618


Vancouver/ICMJE Style

Agubata ZC, Bello K, Omatola C, Adaji B, Olusola AO. Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. J Biol Res Rev. (2025), [cited May 10, 2025]; 2(3): 130-138. doi:10.5455/JBRR.20241025112618


Harvard Style

Agubata, Z. C., Bello, . K., Omatola, . C., Adaji, . B. & Olusola, . A. O. (2025) Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. J Biol Res Rev, 2 (3), 130-138. doi:10.5455/JBRR.20241025112618


Turabian Style

Agubata, Zenas Chisom, Kizito Bello, Cornelius Omatola, Benjamin Adaji, and Ayodele Olubukola Olusola. 2025. Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. Journal of Biological Research and Reviews, 2 (3), 130-138. doi:10.5455/JBRR.20241025112618


Chicago Style

Agubata, Zenas Chisom, Kizito Bello, Cornelius Omatola, Benjamin Adaji, and Ayodele Olubukola Olusola. "Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria." Journal of Biological Research and Reviews 2 (2025), 130-138. doi:10.5455/JBRR.20241025112618


MLA (The Modern Language Association) Style

Agubata, Zenas Chisom, Kizito Bello, Cornelius Omatola, Benjamin Adaji, and Ayodele Olubukola Olusola. "Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria." Journal of Biological Research and Reviews 2.3 (2025), 130-138. Print. doi:10.5455/JBRR.20241025112618


APA (American Psychological Association) Style

Agubata, Z. C., Bello, . K., Omatola, . C., Adaji, . B. & Olusola, . A. O. (2025) Sero-prevalence of Anti-Treponema Antibody Among HIV/AIDS Patients Accessing Anti-Retroviral Drugs at Kogi State Specialist Hospital, Nigeria. Journal of Biological Research and Reviews, 2 (3), 130-138. doi:10.5455/JBRR.20241025112618


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