METHAMPHETAMINE-INDUCED DISSEMINATED INTRAVASCULAR COAGULOPATHY: A CASE REPORT.

Obunmneme Kenechukwu Nwiyi; Sunday Onyemaechi Oriji; Ugochinyere Jane Chilaka; Chilota C Efobi; Justus Uchenna Onu; Richard Uwakwe

doi:10.5455/JMRR.20240820084350

Abstract
Methamphetamine abuse continues to pose a significant public health concern globally, with numerous adverse effects on various body systems. Methamphetamine is a common drug of misuse in Nigeria. It is a derivative of amphetamine, an enantiomer of ephedrine with potent addictive and majorly central nervous system (CNS) stimulating property.
We present a 30-year-old female with a history of chronic methamphetamine misuse who presented to the emergency department of Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, with symptoms consistent with disseminated intravascular coagulopathy (DIC). Despite intensive inpatient management, the patient's condition rapidly deteriorated within 17days duration. This case highlights the intricate interplay between methamphetamine use and the development of DIC, emphasizing the importance of prompt recognition and appropriate management in mitigating adverse outcomes.

Key words: methamphetamine; abuse; misuse; disseminated intravascular coagulopathy; bleeding.